REACH

New substance evaluation conclusions published

• 3-aminophenol (EC 209-711-2, CAS 591-27-5), evaluated by Italy.
• Butanoic acid, 4-amino-4-oxosulfo-, N-coco alkyl derivs., monosodium salts, compds. with triethanolamine (EC 308-662-5, CAS 98171-53-0), evaluated by France.
  
• N-(1,4-dimethylpentyl)-N'-phenylbenzene-1,4-diamine (EC 221-374-3, CAS 3081-01-4) evaluated by Austria.

CLP

Guidance on harmonised information relating to health emergency response updated

We have published an updated version of Guidance on Annex VIII to CLP regulation (version 6.0). It clarifies new provisions in the CLP Regulation.

New proposals and withdrawal to harmonise classification and labelling

Three proposals have been submitted for:

• penoxsulam (ISO); 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzene-1-sulfonamide; 3-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-α,α,α-trifluorotoluene-2-sulfonamide* (EC -, CAS 219714-96-2);
• m-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline* (EC 275-662-9, CAS 71604-74-5) and
• p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline* (EC 225-716-2, CAS 5026-74-4)

A withdrawal has been received for: 

• methyl 4-hydroxybenzoate (EC 202-785-7, CAS 99-76-3)

*Name, EC and CAS number to be confirmed

Consultations on harmonised classification and labelling

We are looking for comments on the harmonised classification and labelling (CLH) proposals for:

• 1-methylimidazole (EC 210-484-7, CAS 616-47-7); and
• imidazole hydrobromide (EC 483-310-2, CAS 101023-55-6)

Have your say until 19 December 2025.

IT Tools

Take a look: New QSAR toolbox video tutorials available

Following the recent update of the QSAR toolbox, we have now published ten video tutorials to help users with the new features of the tool.

 
The OECD QSAR Toolbox is a collaborative project between ECHA, OECD and its member and partner countries. It is used worldwide in hazard assessment of chemicals to avoid unnecessary animal testing.

EU Observatory for Nanomaterials (EUON)

Survey on health and environmental hazards and risks of surface treated nanomaterials

The Nanotechnology Industries Association and Yordas Group have been contracted by the EUON to undertake a study on the assessment of health and environmental hazards and risks of surface treated nanomaterials. 

We would appreciate your input by sharing your expertise
through a short survey. It will be open until Friday 31 October 2025.

Webinars

Reminder: Consultation on PFAS draft opinion – Guidance for respondents

We are launching a consultation on the draft opinion of our Committee for Socio-Economic Analysis (SEAC) on the proposed EU-wide restriction of per- and polyfluoroalkyl substances (PFAS) after the Committee's meeting in March 2026.

To learn more about the purpose and structure of the consultation, as well as how to prepare your data, join our webinar on 30 October 2025 at 11:00-13:00 Helsinki time. Our experts will be there to answer your questions.

Board of Appeal

Announcement of appeal

The Board of Appeal has published an announcement in case A-008-2025 concerning a follow-up decision to a compliance check.

European Commission

Biocides decisions on Union authorisations

The Commission has granted Union authorisations for:

• the biocidal product family '3025'
• the biocidal product family 'B. Braun Medical Propanol Family'

• the single biocidal product 'ClearKlens wipes based on IPA'.

REACH committee meeting this week - draft agenda available

The European Commission’s REACH Committee will meet on 22 and 23 October 2025.