Welcome to the first differentiated service delivery (DSD) newsletter of 2026 from IAS – the International AIDS Society. This edition spotlights the potential of earlier viral load monitoring in enabling earlier DSD enrolment and support for those who are virally unsuppressed.
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Welcome to the first differentiated service delivery (DSD) newsletter of 2026 from IAS – the International AIDS Society. This edition spotlights the potential of earlier viral load monitoring in enabling earlier DSD enrolment and support for those who are virally unsuppressed.

Why Kenya has shifted the first viral load to three months

By Lazarus Momanyi, National AIDS and STI Control Programme (NASCOP), Ministry of Health, Kenya


In 2021, Kenya decided to update national guidance, shifting the first VL from month six to month three to harmonize monitoring across all populations. The month three VL result is available for review during the clinical encounter at month six. The early integration of dolutegravir (DTG) as the preferred first-line agent in Kenya in 2017 provided the pharmacological foundation for this policy change.


Key lessons learnt from Kenya’s implementation of early VL testing were that an early VL is feasible and does not translate to additional VL requirements or costs. With most clients having transitioned to the more efficacious DTG-based ART, suppression rates are favourable, allowing for early transition to less-intense DSD.


The revised Kenya Integrated Guidelines for HIV, STI and Viral Hepatitis 2026 (forthcoming) represent a strategic pivot toward a more resilient and person-centred HIV response, balancing high-quality clinical care with the realities of a shifting global funding landscape. The revised guidance also expands six-multi-month dispensing of ART and introduces an annual clinical review for clients established on ART. Kenya is further expanding access to VL testing by scaling innovative technologies, such as point-of-care and multiplexing platforms.

Read the full piece

 

Don't miss

DSD policy dashboards on the visit schedule in the first year on HIV treatment


This dashboard combines all clinical reviews, viral load test timing and ART refill visits, as outlined in the national guidelines of 15 countries, to determine the likely visit schedule for the first 12 months on ART.

In most African countries, the first VL is taken six months after starting ART. Results are typically available at the clinical consult thereafter, delaying DSD enrolment and support for those who are unsuppressed, despite guidelines recommending earlier entry. Eswatini, Kenya and South Africa are implementing earlier viral load testing.

 

A retrospective analysis of 2023 HIV guideline implementation in South Africa


This retrospective analysis showed that earlier first viral load testing accelerates DSD enrolment for people newly initiated on antiretroviral therapy.

 

Looking ahead, looking back

Looking ahead …

  • Join us and register for AIDS 2026, the 26th International AIDS Conference, taking place in Rio de Janeiro, Brazil, and virtually on 26-31 July. The IAS DSD team will organize and support four satellite sessions focused on annual clinic visits, service prioritization, advanced HIV disease and digital health.
  • The INTEREST 2026 conference will take place in Dar es Salaam, Tanzania, on 12-15 May. View the programme and register here.
  • Register for the webinar, “Youth-Driven Interventions and Models: Dissecting Quality and Integrated Care at Scale for HIV, TB, Hepatitis, and STI Services”, organized by WHO and partners on 17 March. The webinar will discuss scaling up evidence-based, integrated interventions and models for young people.

Looking back …

  • The 33rd Conference on Retroviruses and Opportunistic Infections (CROI 2026) was held in Denver, USA, from 22 to 25 February. At the opening, Peter Staley, ACT UP veteran, co-founder of TAG and PrEP4All leader, called 2025 an “annus horribilis” for HIV. He condemned the “war on science”, the halted PEPFAR funding and the dismantling of USAID and NIH cuts, and he criticized researchers who removed diversity and equity language from grants. Staley pointed to legal challenges, grassroots mobilization and renewed activism as signs of resilience, urging the HIV community to organize, defend science and push for the restoration of global HIV programmes.
  • View the recording and slides from the IAS Educational Fund webinar, “HIV and NCDs: Innovations in prevention, treatment and policy”.
  • View the recording and slides from CQUIN’s webinar, “Integrating HIV Services into Broader Health Delivery Platforms: Country Experiences from CQUIN”.
  • View resources from the webinar, “WHO guidance for High Quality GC8 Proposals for HIV, TB and RSSH”. The webinar provided a focused briefing for HIV and TB programme managers and other key stakeholders on GC8 priorities aligned with WHO guidance and the Global Fund GC8 information notes for HIV, TB and resilient and sustainable systems for health (RSSH).
  • Read the December 2025 Ritshidze and Treatment Action Campaign National State of Health report, which outlines key issues impacting public health services in South Africa since the PEPFAR disruptions.

 

What we're reading

Home visits and flexible PrEP cut HIV incidence by 70% in rural Kenya and Uganda, Alcorn K, aidsmap, March 2026

This article shares results from the Sustainable East Africa Research in Community Health (SEARCH) study cluster randomized controlled trial in rural Kenya and Uganda, presented at CROI 2026. The enhanced ‘Community Precision Health’ intervention consisted of quarterly home visits and home-based HIV testing plus clinic referrals for HIV prevention and HIV treatment. All participants received HIV education to support them assess their HIV prevention needs. If they anticipated HIV exposure in the near future, they received a clinic referral, where they were offered dynamic choice prevention. This allows users to switch between different options according to their needs. Community health workers in the intervention arm used an app for result reporting and bi-directional referrals and delivered PEP and oral PrEP. By pairing digital tools to coordinate care with tailored HIV services delivered by community health workers and clinicians, overall biomedical prevention coverage was fourfold higher and HIV incidence was reduced by 70%.

Feasibility and Preferences for Home-based Self-Testing for HIV, Diabetes, and Hypertension in Kenya, South Africa, and Zambia, Oliver C et al, Preprint, Nov 2025

This cross-sectional study in Kenya, South Africa and Zambia evaluated the feasibility of home-based testing via a household survey and provision of self-testing tools. It found that home-based self-testing for HIV and blood glucose, along with blood pressure screening, was feasible in peri-urban and rural communities. Among 526 participants, over half had not recently tested for HIV, and new diagnoses of HIV (2%), high blood glucose (4%) and high blood pressure (26%) were made, with most users finding the tests easy to use. The majority preferred home-based testing, suggesting it could expand access to care and improve disease detection in low- and middle-income countries.

Age, sex─and what else? Rethinking priorities to close gaps in the HIV care cascade, Jamieson L et al, J Int AIDS Soc, Feb 2026

The Closing The Gap in HIV Target Achievement project aims to identify and characterize unreached and disengaged sub-populations beyond standard demographics, such as age, sex and geographic area, to recommend targeted policies and interventions. This commentary discusses lessons learnt during a project workshop aimed at identifying sub-populations in Mozambique, South Africa and Zimbabwe. Discussions emphasized the need to consider absolute sub-population size alongside percentages, improve data systems to incorporate context and intersectionality, focus on who is not disengaging from care to allocate resources to those who need more support, and consider trade offs between simple public health approaches and tailored care including offering choice.

Population-level coverage and correlates of enrollment in community-based antiretroviral therapy (ART) refill models following differentiated service delivery scale-up in Africa: a multi-country study, Lukose L et al, AIDS Care, Epub ahead of print, Dec 2025

Community-based ART distribution is a promising strategy to increase HIV treatment accessibility, yet population-level coverage and correlates of enrolment are understudied. This study analysed data from seven Population-based HIV Impact Assessment surveys to identify socio-demographic and clinical correlates of enrolment in community, relative to facility-based, ART models. Findings affirm the potential of community-based refill models to reach populations susceptible to HIV care disengagement, but coverage estimates remain low, indicating implementation barriers.

 

What we're listening to

The Promise of PrEP for HIV


Listen to this PrEP episode of The Threshold, a Foreign Policy podcast. It examines what the rollout of long-acting injectable PrEP will mean for Uganda and the global HIV response. It includes interviews with Flavia Matovu Kiweewa, National Principal Investigator for PURPOSE 1 in Uganda, Director Kenneth Mwehonge, HEPS Uganda Executive, and Wafaa El-Sadr, Founder and Director of ICAP at Columbia University.

 

Get in touch

Do you have content for the next newsletter? We want to hear from you.
Email us at dsd@iasociety.org.


www.differentiatedservicedelivery.org

 

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Photo credits in order of appearance: (1) Foreign Policy

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